25th Annual UCSF Course on Pharmacokinetics for Pharmaceutical Scientists

February 13-17, 2012

Mission Bay Conference Center at UCSF

San Francisco, CA

http://bts.ucsf.edu/pkcourse/

This five-day fundamentals course will emphasize basic principles in pharmacokinetics. Presentations will be delivered via lectures and multiple small-group workshops.

The first three and one-half days of this limited-enrollment course will be devoted to essential pharmacokinetic parameters and how they are employed to summarize and predict temporal relationships. The balance of the course will focus on elective topics. 

TOPICS:                                                                                           

Fundamentals of Pharmacokinetics: Clearance    

Fundamentals of Pharmacokinetics: Distribution  

Absorption I: Concepts & Kinetics          

Absorption II: Factors Influencing Drug Absorption

Multiple Dose Regimens, Mean Residence Time  

Macromolecule Pharmacokinetics

Variability, Individualization & Pharmacogenomics            

Nonlinear Pharmacokinetics

Pharmacokinetics & Pharmacodynamics Modeling          

Renal & Hepatic (Metabolic) Elimination

Application in Clinical Practice

Temporal Relationships after Intravascular Administration

Integration of Kinetic Concepts

Bioequivalence: BCS & BDDCS

Multicompartment Kinetics

WORKSHOPS:

Clearance Concepts                         

Distribution and Intravascular Bolus Kinetics                         

Absorption Concepts and Kinetics                             

Multiple Dosing, MRT, Integration of Kinetic Concepts      

Bioavailability, Multicompartment PK, and/or Variability

Renal and Hepatic Elimination

Constant Rate Input

INSTRUCTORS:

Leslie Z. Benet, UCSF (Course Director)                               

Robert A. Upton, UCSF (Course Director)                              

Maureen Boro, UCSF

Leslie Carstensen Floren, UCSF                                          

Kathleen M. Giacomini, UCSF                                             

Sara R. Kenkare-Mitra, Genentech & UCSF

Deanna L. Kroetz, UCSF                                                     

David Lau, Rigel

Svein Øie, University of Georgia

Miki Park, University of the Pacific

Nancy Sambol, UCSF

James Uchizono, University of the Pacific

Davide Verotta, UCSF

Michael E. Winter, UCSF

Optional Half-day Course:

Introduction to Population Pharmacokinetics

For additional information, including online registration and schedule, please visit http://bts.ucsf.edu/pkcourse/ or contact jaime.kenyon@ucsf.edu.

Please pass along this announcement to any of your colleagues who may be interested in attending.